There are rumors on Twitter that Pearl Jam are planning a stadium (possibly arena shows as well) tour in support of their new album for fall 2013. A performance at Wrigley Field in Chicago seems all but confirmed at this point, but there are rumors of other stadium shows as well including at Fenway Park in Boston and Yankee Stadium in New York. Take this all with a grain of salt, obviously. The last time Pearl Jam toured the United States was their 13 date May 2010 tour.
In November Jeff Ament told me that Pearl Jam had no plans set in stone for 2013 outside of meeting in March, but obviously things could have changed since then (or the rumors regarding non Wrigley Field shows could be BS, we sure hope not).